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Illustrative Agape Rx packaging for Compounded Tirzepatide: a black box and clear glass bottle with professionally printed medication labels, lime-green heart-and-cross logos, and prescription-only labeling.
Illustrative packaging; actual dispensing container may vary.

Prescription only

Compounded Tirzepatide

A prescription GIP and GLP-1 receptor agonist that may be prescribed, together with diet and exercise, when a licensed provider decides it is right for you.

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Available only with a prescription from a licensed provider after a medical review. Finishing a consult does not guarantee a prescription. Results vary.

Important safety information: risk of thyroid C-cell tumors

In studies with rodents, medicines with this active ingredient caused thyroid C-cell tumors, including cancer. It is not known whether this happens in people. Do not use it if you or a family member have ever had medullary thyroid carcinoma (MTC), or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

About this medication

Compounded tirzepatide is prepared by a licensed pharmacy for an individual patient pursuant to a prescription, when a licensed provider determines it is medically appropriate and compounding is permitted by applicable law.

Compounded medications are not FDA-approved. The FDA does not review them for safety, effectiveness, or quality.

How it works

Tirzepatide acts on two natural hormone receptors, GIP and GLP-1, that help control appetite and blood sugar. It can make you feel full sooner and slows how quickly your stomach empties.

How it is used

A once-weekly injection under the skin, given as directed by your provider. The dose is usually increased slowly to help your body adjust.

Do not use if you have

  • A personal or family history of medullary thyroid carcinoma (MTC)
  • Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
  • A known serious allergy to the active ingredient or any other ingredient
  • Pregnancy, plans to become pregnant, or breastfeeding

Common side effects

  • Nausea
  • Diarrhea
  • Vomiting
  • Constipation
  • Stomach pain
  • Indigestion
  • Injection site reactions
  • Tiredness
  • Burping
  • Hair loss
  • Heartburn

Serious side effects

  • Possible risk of thyroid C-cell tumors. Tell your provider right away about a lump or swelling in the neck, trouble swallowing, hoarseness, or shortness of breath.
  • Pancreatitis: severe, ongoing stomach pain that may spread to the back, with or without vomiting.
  • Gallbladder problems, including gallstones.
  • Low blood sugar, especially when used with insulin or sulfonylureas.
  • Kidney problems, often caused by dehydration from nausea, vomiting, or diarrhea.
  • Serious allergic reactions, such as swelling of the face, lips, tongue, or throat, trouble breathing, or severe rash.
  • Changes in vision in people with type 2 diabetes.
  • Depression or thoughts of suicide. Report any new or worsening mood changes.
  • Food or liquid getting into the lungs (aspiration) during anesthesia or sedation. Tell every provider that you take this medicine before any procedure.

Drug interactions

  • Insulin or sulfonylureas (higher risk of low blood sugar)
  • Oral medicines, including birth control pills, may work less well. Use a non-oral or backup birth control method for 4 weeks after starting and after each dose increase.
  • Do not use with other GLP-1 receptor agonist medicines

Tell your provider about all the medicines, vitamins, and supplements you take.

This is not a complete list of side effects or risks. Talk to your provider about your medical history. If you have a medical emergency, call 911. You can report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Prescriptions are written by independent licensed providers through LocumTele and filled by Rush Pharmacy, a licensed pharmacy. See our compounded medication disclosure.

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A prescription is never guaranteed. Eligibility is determined by a licensed medical provider.